Tom N. Grossman
VU University Amsterdam
Research in the Grossman group centers around the synthesis of peptide-derived molecules and the engineering of proteins using organic reactions. Central aspects are the synthesis of non-natural amino acids as well as modified peptides, and the use of biocompatible reactions for the selective functionalization of unprotected peptides and proteins. For example, the group uses these techniques for the development of novel bioactive peptidomimetics and for chemical protein/enzyme engineering.